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Articles (210)
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Stage at which riluzole treatment prolongs survival in patients with amyotrophic lateral sclerosis: a retrospective analysis of data from a dose-ranging study

Fang, Ton, Al Khleifat, Ahmad, Meurgey, Jacques-Henri, Jones, Ashley, Leigh, P Nigel, Bensimon, Gilbert, Al-Chalabi, Ammar

Journal:

The Lancet Neurology

Année:

2018

Langue:

english

Fichier:

PDF, 268 KB

english, 2018

The influence of the environment on adventure tourism: from motivations to experiences

Giddy, Julia Kathryn, Webb, Nigel Leigh

Journal:

Current Issues in Tourism

Année:

2016

Langue:

english

Fichier:

PDF, 557 KB

english, 2016

Can bans stimulate wildlife trade?

Rivalan, Philippe, Delmas, Virginie, Angulo, Elena, Bull, Leigh S., Hall, Richard J., Courchamp, Franck, Rosser, Alison M., Leader-Williams, Nigel

Journal:

Nature

Année:

2007

Langue:

english

Fichier:

PDF, 413 KB

english, 2007

Clinical Trials in ALS: An Overview

Turner, Martin R., Parton, Matthew J, Leigh, P. Nigel

Journal:

Seminars in Neurology

Année:

2001

Langue:

english

Fichier:

PDF, 352 KB

english, 2001

Occasional essay: Upper motor neuron syndrome in amyotrophic lateral sclerosis

Swash, Michael, Burke, David, Turner, Martin R, Grosskreutz, Julian, Leigh, P Nigel, deCarvalho, Mamede, Kiernan, Matthew C

Journal:

Journal of Neurology Neurosurgery & Psychiatry

Année:

2020

Fichier:

PDF, 563 KB

2020

Functional magnetic resonance imaging of verbal fluency and confrontation naming using compressed image acquisition to permit overt responses

Sharon Abrahams, Laura H. Goldstein, Andy Simmons, Michael J. Brammer, Steve C.R. Williams, Vincent P. Giampietro, Chris M. Andrew, P. Nigel Leigh

Journal:

Human Brain Mapping

Année:

2003

Langue:

english

Fichier:

PDF, 251 KB

english, 2003

A novel central motor conduction abnormality in D90A-homozygous patients with amyotrophic lateral sclerosis

Abena D. Osei-Lah, Martin R. Turner, Peter M. Andersen, P. Nigel Leigh, Kerry R. Mills

Journal:

Muscle & Nerve

Année:

2004

Langue:

english

Fichier:

PDF, 134 KB

english, 2004

Using complementary DNA from MyoD-transduced fibroblasts to sequence large muscle genes

Leigh B. Waddell, Nicole Monnier, Sandra T. Cooper, Kathryn N. North, Nigel F. Clarke

Journal:

Muscle & Nerve

Année:

2011

Langue:

english

Fichier:

PDF, 149 KB

english, 2011

Issues & opinion. Neurofilaments, free radicals, excitotoxins, and amyotrophic lateral sclerosis

Ammar Al-Chalabi, John F. Powell, P. Nigel Leigh

Journal:

Muscle & Nerve

Année:

1995

Langue:

english

Fichier:

PDF, 563 KB

english, 1995

Living with motor neurone disease: lives, experiences of services and suggestions for change

Rhidian A. Hughes, Anu Sinha, Irene Higginson, Keren Down, P. Nigel Leigh

Journal:

Health & Social Care in the Community

Année:

2005

Langue:

english

Fichier:

PDF, 141 KB

english, 2005

Online Analysis of Functional MRI Datasets on Parallel Platforms

Nigel Goddard, Greg Hood, Jonathan Cohen, William Eddy, Christopher Genovese, Douglas Noll, Leigh Nystrom

Journal:

The Journal of Supercomputing

Année:

1997

Fichier:

PDF, 1.26 MB

1997

Motor neurone disease: A review of its emotional and cognitive consequences for patients and its impact on carers

Laura H. Goldstein, P. Nigel Leigh

Journal:

British Journal of Health Psychology

Année:

1999

Langue:

english

Fichier:

PDF, 175 KB

english, 1999

Novel FLNC mutation in a patient with myofibrillar myopathy in combination with late-onset cerebellar ataxia

Giorgio Tasca, Zagaa Odgerel, Mauro Monforte, Stefania Aurino, Nigel F. Clarke, Leigh B. Waddell, Bjarne Udd, Enzo Ricci, Lev G. Goldfarb

Journal:

Muscle & Nerve

Année:

2012

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2012

Biomarkers in amyotrophic lateral sclerosis

Martin R Turner, Matthew C Kiernan, P Nigel Leigh, Kevin Talbot

Journal:

The Lancet Neurology

Année:

2009

Langue:

english

Fichier:

PDF, 734 KB

english, 2009

Mutations in the gene encoding human persyn are not associated with amyotrophic lateral sclerosis or familial Parkinson's disease

Joanna M Flowers, P.Nigel Leigh, Alun M Davies, Natalia N Ninkina, Vladimir L Buchman, Jenny Vaughan, Nick W Wood, John F Powell

Journal:

Neuroscience Letters

Année:

1999

Langue:

english

Fichier:

PDF, 80 KB

english, 1999

Good practice in the management of amyotrophic lateral sclerosis: Clinical guidelines. An evidence‐based review with good practice points. EALSC Working Group

Andersen, Peter Munch, Borasio, Gian Domenico, Dengler, Reinhard, Hardiman, Orla, Kollewe, Katja, Leigh, Peter Nigel, Pradat, Pierre‐Francois, Silani, Vincenzo, Tomik, Barbara

Journal:

Amyotrophic Lateral Sclerosis

Année:

2007

Langue:

english

Fichier:

PDF, 559 KB

english, 2007

Consensus criteria for the diagnosis of frontotemporal cognitive and behavioural syndromes in amyotrophic lateral sclerosis

Strong, Michael J., Grace, Gloria M., Freedman, Morris, Lomen-Hoerth, Cathy, Woolley, Susan, Goldstein, Laura H., Murphy, Jennifer, Shoesmith, Christen, Rosenfeld, Jeffery, Leigh, P. Nigel, Bruijn, Lu

Journal:

Amyotrophic Lateral Sclerosis

Année:

2009

Langue:

english

Fichier:

PDF, 216 KB

english, 2009

Patients' health-related quality of life and utilities associated with different stages of amyotrophic lateral sclerosis

Gwendoline M Kiebert, Colin Green, Caroline Murphy, J.Douglas Mitchell, Mary O'Brien, Anita Burrell, P.Nigel Leigh

Journal:

Journal of the Neurological Sciences

Année:

2001

Langue:

english

Fichier:

PDF, 91 KB

english, 2001

Amyotrophic lateral sclerosis

Lokesh C Wijesekera, P Nigel Leigh

Journal:

Orphanet Journal of Rare Diseases

Année:

2009

Langue:

english

Fichier:

PDF, 1.90 MB

english, 2009

Getting it Wrong: The Cinema of Norman Mailer

Leigh, Nigel

Journal:

Journal of American Studies

Année:

1990

Langue:

english

Fichier:

PDF, 679 KB

english, 1990

Spirit of Place in Mailer's The Naked and the Dead

Leigh, Nigel

Journal:

Journal of American Studies

Année:

1987

Langue:

english

Fichier:

PDF, 747 KB

english, 1987

Behavioural and emotional symptoms of apathy are associated with distinct patterns of brain atrophy in neurodegenerative disorders

Biba R. Stanton, P. Nigel Leigh, Robert J. Howard, Gareth J. Barker…

Journal:

Journal of Neurology

Année:

2013

Langue:

english

Fichier:

PDF, 517 KB

english, 2013

Estimating clinical stage of amyotrophic lateral sclerosis from the ALS Functional Rating Scale

Balendra, Rubika, Jones, Ashley, Jivraj, Naheed, Knights, Catherine, Ellis, Catherine M., Burman, Rachel, Turner, Martin R., Leigh, P. Nigel, Shaw, Christopher E., Al-Chalabi, Ammar

Journal:

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Année:

2014

Langue:

english

Fichier:

PDF, 71 KB

english, 2014

Genetic and epigenetic studies of amyotrophic lateral sclerosis

Al-Chalabi, Ammar, Kwak, Shin, Mehler, Mark, Rouleau, Guy, Siddique, Teepu, Strong, Michael, Leigh, Peter Nigel

Journal:

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Année:

2013

Langue:

english

Fichier:

PDF, 124 KB

english, 2013

The risk to relatives of patients with sporadic amyotrophic lateral sclerosis

Hanby, M. F., Scott, K. M., Scotton, W., Wijesekera, L., Mole, T., Ellis, C. E., Nigel Leigh, P., Shaw, C. E., Al-Chalabi, A.

Journal:

Brain

Année:

2011

Langue:

english

Fichier:

PDF, 107 KB

english, 2011

Radical Fictions and the Novels of Norman Mailer || The Dilemma of Power in The Naked and the Dead

Leigh, Nigel

Année:

1990

Langue:

english

Fichier:

PDF, 3.30 MB

english, 1990

Stem Cell Therapy for ALS: Hope and RealityA discussion paper from the Executive of the European ALS Consortium

Silani, Vincenzo, Leigh, Nigel

Journal:

Amyotrophic Lateral Sclerosis

Année:

2003

Langue:

english

Fichier:

PDF, 205 KB

english, 2003

Targeted Re-Sequencing Emulsion PCR Panel for Myopathies: Results in 94 Cases

Punetha, Jaya, Kesari, Akanchha, Uapinyoying, Prech, Giri, Mamta, Clarke, Nigel F., Waddell, Leigh B., North, Kathryn N., Ghaoui, Roula, O’Grady, Gina L., Oates, Emily C., Sandaradura, Sarah A., Bönne

Journal:

Journal of Neuromuscular Diseases

Année:

2016

Langue:

english

Fichier:

PDF, 808 KB

english, 2016

Multimorbidity and polypharmacy in diabetic patients with NAFLD

Patel, Preya Janubhai, Hayward, Kelly Lee, Rudra, Rathiga, Horsfall, Leigh Ula, Hossain, Fabrina, Williams, Suzanne, Johnson, Tracey, Brown, Nigel Neil, Saad, Nivene, Clouston, Andrew Donald, Stuart,

Journal:

Medicine (Medicine Publishing Company Ltd)

Année:

2017

Langue:

english

Fichier:

PDF, 378 KB

english, 2017

The benefit of evolving multidisciplinary care in ALS: a diagnostic cohort survival comparison

Martin, Sarah, Trevor-Jones, Emma, Khan, Sabyha, Shaw, Keelan, Marchment, Deepti, Kulka, Anna, Ellis, Catherine E, Burman, Rachel, Turner, Martin R., Carroll, Liam, Mursaleen, Leah, Leigh, P. Nigel, S

Journal:

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Année:

2017

Langue:

english

Fichier:

PDF, 847 KB

english, 2017

Stage of prolonged survival in ALS – Author's reply

Al-Chalabi, Ammar, Fang, Ton, Khleifat, Ahmad Al, Meurgey, Jacques-Henri, Jones, Ashley, Leigh, P Nigel, Bensimon, Gilbert

Journal:

The Lancet Neurology

Année:

2018

Langue:

english

Fichier:

PDF, 45 KB

english, 2018

Paramedics’ experiences of administering fascia iliaca compartment block to patients in South Wales with suspected hip fracture at the scene of injury: results of focus groups

Evans, Bridie Angela, Brown, Alan, Bulger, Jenna, Fegan, Greg, Ford, Simon, Guy, Katy, Jones, SIan, Keen, Leigh, Khanom, Ashrafunnesa, Longo, Mirella, Pallister, Ian, Rees, Nigel, Russell, Ian T, Seag

Journal:

BMJ Open

Année:

2019

Langue:

english

Fichier:

PDF, 291 KB

english, 2019

Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: ASCO Clinical Practice Guideline Update

Key, Nigel S., Khorana, Alok A., Kuderer, Nicole M., Bohlke, Kari, Lee, Agnes Y.Y., Arcelus, Juan I., Wong, Sandra L., Balaban, Edward P., Flowers, Christopher R., Francis, Charles W., Gates, Leigh E.

Journal:

Journal of Clinical Oncology

Année:

2019

Langue:

english

Fichier:

PDF, 690 KB

english, 2019

Expectations and experiences of psychological therapy from the client perspective: a qualitative study

Brooks, Joanna, Bratley, Rachael, Jones, Leigh, King, Nigel, Lucock, Mike

Journal:

British Journal of Guidance & Counselling

Année:

2020

Langue:

english

Fichier:

PDF, 1006 KB

english, 2020

Intron 7 retention and exon 9 skipping EAAT2 mRNA variants are not associated with amyotrophic lateral sclerosis

Joanna M. Flowers, John F. Powell, P. Nigel Leigh, Peter Andersen, Christopher E. Shaw

Journal:

Annals of Neurology

Année:

2001

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2001

Cuznsod-associated amyotrophic lateral sclerosis

Aleksandar Radunovic, Christopher E. Shaw, Gülsen Akman-Demir, H. Idrisoglu, P. Nigel Leigh

Journal:

Annals of Neurology

Année:

1997

Langue:

english

Fichier:

PDF, 227 KB

english, 1997

The bridge between neurology and psychiatry. Edited By E. H. Reynolds and M. R. Trimble. Churchill Livingstone, Edinburgh, 1989. Price: £47.50

Nigel Leigh

Journal:

International Journal of Geriatric Psychiatry

Année:

1991

Langue:

english

Fichier:

PDF, 116 KB

english, 1991

Recessive mutations in RYR1 are a common cause of congenital fiber type disproportion

Nigel F. Clarke, Leigh B. Waddell, Sandra T. Cooper, Margaret Perry, Robert L.L. Smith, Andrew J. Kornberg, Francesco Muntoni, Suzanne Lillis, Volker Straub, Kate Bushby, Michela Guglieri, Mary D. Kin

Journal:

Human Mutation

Année:

2010

Langue:

english

Fichier:

PDF, 531 KB

english, 2010

D90A-SOD1 mediated amyotrophic lateral sclerosis: A single founder for all cases with evidence for a Cis-acting disease modifier in the recessive haplotype

Matthew J. Parton, Wendy Broom, Peter M. Andersen, Ammar Al-Chalabi, P. Nigel Leigh, John F. Powell, Christopher E. Shaw

Journal:

Human Mutation

Année:

2002

Langue:

english

Fichier:

PDF, 103 KB

english, 2002

Neuroserpin regulates N-cadherin-mediated cell adhesion independently of its activity as an inhibitor of tissue plasminogen activator

Tet Woo Lee, Leigh C. Coates, Nigel P. Birch

Journal:

Journal of Neuroscience Research

Année:

2008

Langue:

english

Fichier:

PDF, 556 KB

english, 2008

Posttranslational Maturation of the Prohormone Convertase SPC3 In Vitro

Leigh C. Coates, Nigel P. Birch

Journal:

Journal of Neurochemistry

Année:

1997

Langue:

english

Fichier:

PDF, 879 KB

english, 1997

Differential Cleavage of Provasopressin by the Major Molecular Forms of SPC3

Leigh C. Coates, Nigel P. Birch

Journal:

Journal of Neurochemistry

Année:

1998

Langue:

english

Fichier:

PDF, 1.23 MB

english, 1998

Androgen-induced up-regulation of tubulin isoforms in neuroblastoma cells

Rachel Butler, P. Nigel Leigh, Jean-Marc Gallo

Journal:

Journal of Neurochemistry

Année:

2001

Langue:

english

Fichier:

PDF, 441 KB

english, 2001

Neuroserpin regulates neurite outgrowth in nerve growth factor-treated PC12 cells

Parmjeet K. Parmar, Leigh C. Coates, John F. Pearson, Rena M. Hill, Nigel P. Birch

Journal:

Journal of Neurochemistry

Année:

2002

Langue:

english

Fichier:

PDF, 391 KB

english, 2002

riluzole and motor neuron disease

Martin A. Turner, Ammar Al-Chalabi, Christopher E. Shaw, P. Nigel Leigh

Journal:

Practical Neurology

Année:

2003

Langue:

english

Fichier:

PDF, 117 KB

english, 2003

Protocol for a double-blind randomised placebo-controlled trial of lithium carbonate in patients with amyotrophic Lateral Sclerosis (LiCALS) [Eudract number: 2008-006891-31]

Ammar Al-Chalabi, Pamela J Shaw, Carolyn A Young, Karen E Morrison, Caroline Murphy, Marie Thornhill, Joanna Kelly, I Nicholas Steen, P Nigel Leigh, on behalf of UKMND-LiCALS

Journal:

BMC Neurology

Année:

2011

Langue:

english

Fichier:

PDF, 223 KB

english, 2011

Type VII collagen antibody LH 7.2 identifies basement membrane characteristics of thin malignant melanomas

Dr Nigel Kirkham, Margaret L. Price, Barry Gibson, Irene M. Leigh, Peter Coburn, Charles R. Darley

Journal:

The Journal of Pathology

Année:

1989

Langue:

english

Fichier:

PDF, 505 KB

english, 1989

Improving communication between service users and professionals via the internet

Dr Rhidian Hughes, Irene Higginson, Anu Sinha, Keren Down, Nigel Leigh

Journal:

Practice Development in Health Care

Année:

2004

Langue:

english

Fichier:

PDF, 180 KB

english, 2004

Amyotrophic lateral sclerosis in an urban setting

Clare A. Johnston, Biba R. Stanton, Martin R. Turner, Rebecca Gray, Ashley Hay-Ming Blunt, David Butt, Mary-Ann Ampong, Christopher E. Shaw, P. Nigel Leigh, Ammar Al-Chalabi

Journal:

Journal of Neurology

Année:

2006

Langue:

english

Fichier:

PDF, 49 KB

english, 2006

Cortical involvement in four cases of primary lateral sclerosis using [11C]-flumazenil PET

Martin R. Turner, Alexander Hammers, Ammar Al-Chalabi, Christopher E. Shaw, Peter M. Andersen, David J. Brooks, P. Nigel Leigh

Journal:

Journal of Neurology

Année:

2007

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2007